Research Project/Study Participation – 2004 to Present:

 

  • Fontan outcomes in Hypoplastic Left Heart Syndrome. Relationship to the method of Stage-1 palliation. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 04/27/2015 (Still Active)
  • Fontan outcomes and pulmonary blood flow at birth. Sponsored by Children’s Heart Center, Las Vegas, NV. Started on 04/09/2015 (Still Active)
  • ON-X Prosthetic Heart Valve – Sizes 19mm Aortic and 23mm Mitral. Sponsored by ON-X Life Technologies Inc. and Children’s Heart Center, and Sunrise Hospital and Medical Center, Las Vegas, Nevada. Started on 01/07/2015. (Still Active)
  • Descriptive comparative study of the presence of exercise induced bronchospasm and adherence to standardized exercise/dietary intervention between asthmatic and non asthmatic children with high body mass index. Sponsored by Children’s Heart Center and UNLV, Las Vegas, Nevada. Started on 11/05/2014. (Still active)
  • Fontan Hepatic Fibrosis and Pulmonary Vascular Development. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 10/01/2014. (Closed on 05/06/2015)
  • Heterotaxy in Southern Nevada: Prenatal Detection and Epidemiology. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 10/01/2014. (Closed on 05/06/2015)
  • Dexmedetomidine and post-operative Arrhythmia in congenital heart disease. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 08/06/2014. (Still active)
  • Assessment of Urine Heparanase Levels in Patients with Pulmonary Hypertension. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 12/13/2013. (Still active)
  • Electrocardiogram Feasibility of the Subcutaneous Defibrillator in Congenital Heart Disease. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 12/04/2013. (Still active)
  • Cardiac Arrhythmias in patients after hybrid procedure for correction of single ventricle disease. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 06/13/2013. (Still active)
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  • Long term, single-arm, open-label extension study of protocol AC-055-305 to assess the safety, tolerability and efficacy of Macitentan in subjects with Eisenmenger Syndrome. Sponsored by Actelion Clinical Research, Inc. and Children’s Heart Center, Las Vegas, Nevada. Started 06/13/2013. (Still active)
  • Pulmonary Artery Repair with Covered Stents (PARCS). Sponsored by Johns Hopkins University, and Children’s Heart Center and Sunrise Hospital and Medical Center, Las Vegas, Nevada. Started on 04/13/2013. (Still active)
  • A multi-center, double blind, randomized placebo-controlled, parallel-group, Phase 3 study to evaluate the effects of macitentan on exercise capacity in subjects with Eisenmenger Syndrome. Sponsored by Actelion Clinical Research, Inc. and Children’s Heart Center, Las Vegas, Nevada. Started on 04/13/2013. (Still active)
  • Eisenmenger Quality Enhancement Research Initiative (QuERI). Sponsored by Actelion Pharmaceuticals US, Inc. Children’s Heart Center, Las Vegas, Nevada. Started on 06/11/2012. (Still active)
  • Adult Congenital Heart Disease (ACHD) Quality Enhancement Research Initiative (QuERI). Sponsored by Actelion Pharmaceuticals US, Inc. Children’s Heart Center, Las Vegas, Nevada. Started on 04/30/2012. (Still active)
  • Medtronic Contegra Tissue Valve/Conduit. Sponsored by Medtronic Cardiovascular Lifeline and Children’s Heart Center and Sunrise Medical Center. Las Vegas, Nevada. Started on 01/04/2012. (Still active)
  • Prenatal cardiac intervention in fetuses with aortic valve stenosis, hypoplastic left heart syndrome and inadequate atrial septal defect or pulmonary valve stenosis/atresia and intact ventricular septum. Children’s Heart Center and Sunrise Hospital and Medical Center, Las Vegas, Nevada. Started on 03/25/2011. (Still active)
  • Management of a right ventricular outflow tract conduit dysfunction with the Melody transcatheter pulmonary valve. Sponsored by AGA Medical Corporation. Children’s Heart Center and Sunrise Hospital and Medical Center, Las Vegas, Nevada. Started on 07/2010. (Still active)
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  • Closure of Muscular Ventricular Septal Defects with the AMPLATZER Muscular VSD Occluder. Sponsored by St Jude Medical, Inc. Children’s Heart Center, and Sunrise Hospital and Medical Center. Las Vegas, Nevada. Started on 05/01/2009. (Still active)
  • Changes in Perception of Health and Behavior in Overweight Children and Adolescents Following Attendance of a Medically Supervised Summer Camp. Children’s Heart Center, Las Vegas, Nevada. Started on 05/2007 (Closed on 4/2012)
  • Prospective Randomized investigation to Evaluate incidence of headache reduction in subjects with Migraine and PFO Using the AMPLATZER PFO Occluder compared to Medical Management. Sponsored by AGA Medical Corporation. Children’s Heart Center, Las Vegas, Nevada. Started on 03/2007. (Still active. Pending closure)
  • A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Arm Study Assessing the Efficacy, Safety, and Dose-Response of Ramipril for the Treatment of Hypertension in Children and Adolescents. Sponsored by King Pharmaceutical, Inc. Children’s Heart Center, Las Vegas, Nevada. Started on 02/2007 (Closed on 12/2007)
  • Changes in Parental Perception of Health and Behavior in Children and Adolescents with Congenital/Acquired Heart Diseases Following Attendance a Medically Supervised Summer Camp. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 05/2006 (Closed on 4/2012)
  • Quantification of levels of urine isoprostanes as indices of oxidant stress in overweight children and adolescents. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 05/2006 (Closed on 11/2006)
  • Evaluation of safety and efficacy of Omega-3 fish oil dietary supplementation in biometric measurement, lipid profile, serum markers for inflammation, and insulin resistance in overweight children and adolescents. Sponsored by Children’s Heart Center (Las Vegas, NV, USA) and Sears Laboratories (Danvers, MA, USA). Started on 02/2006 (Closed on 07/2010)
  • Long-term impact of a medically supervised risk factor reduction program on body mass index (BMI) and weekly physical activity in overweight children and adolescents. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 01/2006 (Closed on 06/2010)
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  • Cardiolite-301: A phase III, open label, non-randomized, international, multicenter trial to evaluate the efficacy and safety of Cardiolite® myocardial perfusion imaging in pediatric subjects with Kawasaki disease. Sponsored by Bristol-Myers Squibb. Children’s Heart Center and Sunrise Hospital, Las Vegas, Nevada. Started on 01/2006 (Closed on 10/2006)
  • A prospective, multicenter, randomized controlled trial to evaluate the safety and efficacy of the Starflex® Septal closure system versus best medical therapy in patients with a stroke and/or transient ischemic attack due to presumed paradoxical embolism through a patent foramen ovale. Multicenter Nationwide Clinical Trial. Sponsored by NMT Medical Inc. Children’s Heart Center and Sunrise Hospital, Las Vegas, Nevada. Started on 08/2005 (Closed on 11/2010)
  • Dose-Ranging Study to Evaluate the Safety and Efficacy of Olmesartan Medoxomil in Children and Adolescents with Hypertension. Sponsored by Sankyo Inc. and Children’s Heart Center, Las Vegas, Nevada. Started on 04/2005 (Closed on 06/2008)
  • Gene and protein changes in porcine models of pulmonary vascular disease. Sponsored by Children’s Heart Center and UNLV, Las Vegas, Nevada. Started on 11/2004. (Still active)
  • An ongoing evaluation of the safety and efficacy of the Cardioseal™ Septal occlusion system with Qwik® Load in patients with ventricular septal defect  (post –market VSD follow-up registry) Multicenter Nationwide Clinical Trial sponsored by NMT Medical Inc. Sponsored by Children’s Heart Center, in Las Vegas, Nevada. Started on 07/2004 (Closed on 01/2006)
  • Brachial reactivity in obese children. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 05/2004 (Closed on 10/2007)
  • Brain natriuretic peptide, troponin I, myoglobin and creatine- kinase MB following interventional cardiac catheterization in patients with congenital heart disease. Sponsored by Children’s Heart Center, Las Vegas, Nevada. Started on 02/2004 (Closed on 09/2010)
  • Omega-3 fish oil dietary supplement in obese children. Sponsored by Children’s Heart Center (Las Vegas, NV, USA) and Sears Laboratories (Danvers, MA, USA). Started on 07/2003 (Closed on 03/2006)
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