© 2021 Wiley Periodicals LLC

Journal of Cardiac Surgery (2021) vol 36(4):1381-1388

DOI: 10.1111/jocs.15414

Received: 11 August 2020 / Accepted: 31 August 2020


Isolated vascular rings in the era of high prenatal detection rates: Demographics, diagnosis, risk factors, and outcome



William N Evans, MD, Ruben J Acherman, MD, Michael L Ciccolo, MD, Juan Lehoux, MD, Dean Berthoty, MD, Gary A Mayman, MD, Humberto Restrepo, MD, MPH



Children’s Heart Center Nevada, 3006 S Maryland Parkway, Ste 690, Las Vegas, NV 89109, USA. Email: WNevans50@aol.com.



Objective: We reviewed our center's isolated vascular ring data.


Methods: Inclusion criteria were patients born in Nevada between June 2015 and July 2020 with situs solitus, levocardia, atrioventricular and ventriculoarterial con-cordance, and no significant intracardiac malformations.


Results: We identified 95 patients. Of the 95, 56 (59%) were female (p = .033). For the study period, there were approximately 180,000 live births, for a prevalence of 5.3 isolated vascular rings per 10,000 live births. Of the 95, 78 (82%) were prenatally diagnosed. Of the 95, 63 (66%) were products of highrisk pregnancies (p = .0001). Additionally, we found advanced maternal age was an isolated vascular ring risk factor (relative risk ratio, 2.7; 95% confidence interval, 1.8, 4.1; p < .00001).


Conclusions: Isolated vascular rings are relatively common cardiovascular malformations and more common in females. High prenatal detection rates are achievable. Further, the majority with isolated vascular rings are products of highrisk pregnancies, and advanced maternal age is a statistically significant occurrence risk factor.


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