© 2014 Wiley Periodicals, Inc. Congenit Heart Dis. 2014

An Increased Incidence of Total Anomalous Pulmonary Venous Connection among Hispanics in Southern Nevada



William N Evans, MD, Ruben J Acherman, MD, Michael L Ciccolo, MD, William J Castillo, MD,  and Humberto Restrepo, MD, MPH



Children’s Heart Center Nevada, 3006 S Maryland Pkwy, Ste 690, Las Vegas, Nevada 89109, USA. Email: hurescan@gmail.com.



Objective -Ethnicity may influence the occurrence of specific cardiac malformations.


Design - We retrospectively analyzed the occurrence of isolated total anomalous pulmonary venous connection in the Hispanic and non-Hispanic populations of Southern Nevada over a 10-year period from 2003 to 2013.


Results - The mean cases per 100 000 live births among Hispanics was 19.8 (99% confidence interval 5.9–33.7) and among non-Hispanics was 2.5 (99% confidence interval 0.4–4.6), P = 0.007.


Conclusions - We found a significantly higher incidence of isolated total anomalous pulmonary venous connection in Hispanics vs. non-Hispanics.


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