Received: 4 September 2014 / Accepted: 7 January 2015

© Springer Science+Business Media New York 2015

Pediatr Cardiol

DOI 10.1007/s00246-015-1099-3

Heterotaxy in Southern Nevada: Prenatal Detection and Epidemiology



William N Evans, MD, Ruben J Acherman, MD, Humberto Restrepo, MD, MPH



ChildrenŐs Heart Center Nevada, 3006 S Maryland Pkwy, Ste 690, Las Vegas, Nevada 89109, USA. Email:



We retrospectively analyzed a combination of prenatally detected and postnatally diagnosed patients with heterotaxic situs that included those with situs inversus, bilateral left-sidedness, and bilateral right-sidedness for the period between April 2002 and July 2014. We found a statistically higher prevalence in the Hispanic population of Southern Nevada of 2.7/10,000 live births (95 % confidence intervals of 1.7–3.9) versus the non-Hispanic population of 1.6/10,000 live births (95 % confidence intervals of 1.1–2.1), p = 0.04. Additionally, we noted a high prenatal detection rate of 68 % over the 12-year period of time, rising to 100 % over the last 2 years.


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