Pediatr Cardiol

DOI 10.1007/s00246-016-1403-x

Received: 6 January 2016 / Accepted: 22 April 2016

© Springer Science+Business Media New York 2016


An Observation from Liver Biopsies Two Decades Post-Fontan



Sergio A Carrillo, MD1,2, Alvaro Galindo, MD1,2, Abraham Rothman, MD1,2, Brody J Winn, MD3, Noel S. Yumiaco, MD3, Humberto Restrepo, MD, MPH1,2


1 - ChildrenŐs Heart Center Nevada, 3006 S. Maryland Pkwy, Ste. 690, Las Vegas, NV 89109, USA; 2 - Division of Pediatric Cardiology, Department of Pediatrics, University of Nevada School of Medicine, 2040 W. Charleston Blvd Ste. 402, Las Vegas, NV 89109, USA; 3 - Laboratory Medicine Consultants, Las Vegas, NV, USA



ChildrenŐs Heart Center Nevada, 3006 S Maryland Pkwy, Ste 690, Las Vegas, Nevada 89109, USA. Email:



This brief report describes an observation from liver biopsy results in nonfailing Fontan patients, currently in their second postoperative decade. In three patients, with either atriopulmonary or atrioventricular connections and functional left ventricles, we found no portal fibrosis. In contrast, we found portal fibrosis in three clinically similar, nonfailing Fontan patients with lateral tunnel connections and functional left ventricles. We recognize the results may be secondary to chance; nevertheless, we speculate about possible relevancy.


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